Pure Gallbladder Squamous Cell Carcinoma With Metastasis To The Liver: An Incidental Finding

A Case Report

  • Khashayar Farzam University of New England College of Osteopathic Medicine
  • Victor Tin


Squamous cell carcinoma of the gallbladder is a rare malignancy that represents 1-2% of gallbladder cancer diagnoses. Given its vague clinical manifestations, it is often diagnosed at an advanced stage. Treatment is challenging given the rarity and aggressiveness of this cancer and the lack of literature supporting various treatment options. Surgical resection, if possible, is the primary first-line treatment in addition to chemotherapy both as adjuvant therapy and palliative care. This case report presents a 77-year-old African-American male with vague gastrointestinal complaints. Computed tomography revealed small bowel obstruction and lesions suspicious for malignancy in the gallbladder and liver. The patient was taken to the operating room for lysis of bowel adhesions and subsequent gallbladder and liver biopsies revealed squamous cell carcinoma of the gallbladder with metastasis to the liver. This case report shows that squamous cell carcinoma of the gallbladder should be considered for the differential of any biliary system pathology.